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We showed that extra-mitochondrial WT PINK1 inhibit tyrosine hydroxylase (TH) and down regulate DA level in DA neurons, whereas pathogenic PINK1 mutations up-regulate TH activity and DA content in DA neurons

DeCasien, A

Suberosin alleviates thiazolidinedione-induced cardiomyopathy in diabetic rats by inhibiting ferroptosis via modulation of ACSL4-LPCAT3 and PI3K-AKT signaling pathways

Our findings reveal that the D4.7R has weaker maximal PLM activity compared to D4.2R and D4.4R