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The clinical efficacy of combining active Folate and Vitamin B12 is robustly supported by literature, particularly in the realm of peripheral neuropathy

Food Sci Human Well 13:34343446 Paul B, Snyder S (2010) The unusual amino acid l-ergothioneine is a physiologic cytoprotectant

Where the Science Still Has Gaps Several questions remain unresolved: optimal dosing for therapeutic applications long-term systemic safety standardized clinical protocols large randomized human trials These gaps highlight the difference between promising experimental science and established clinical practice

Updated 4/2/2020

[DOI] [PubMed] [Google Scholar] 56.Mzsik G