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In a mouse model, this approach significantly lowered blood low-density lipoprotein (LDL) cholesterol, demonstrating LNP-Cas9s potential in treating FH [278]
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doi: 10.1016/j.lfs.2009.02.026 63 KimAHSonD-HMoonM-EJeonSLeeHSLeeY-J

10.7150/thno.51777 16 ChenS.LuK.HouY.YouZ.ShuC.WeiX.et al (2023)
Martini G, Ursini MV (1996) A new lease of life for an old enzyme
