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doi:10.1016/j.cnp.2019.01.005 Venhovens J, Meulstee J, Verhagen WIM
Also, with the current high level of concern about possible skin damage from sun exposure, many people cover up or use so much sunscreen that the sun cannot access their skin to make vitamin D3
The systemic inflammation underlying psoriasis can also manifest as psoriatic arthritis, a potentially severe arthritic joint condition
Aside from its role in catecholamine catabolism, COMT converts an antiestrogen compound (2-hydroxyestradiol) to a proestrogen (2-methoxyestradiol) and leads to an estrogen-rich environment
Biologic response modifiers
