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Agamah, F
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SAMA (e.g., ipratropium): onset within 1530 minutes, lasts 46 hours LAMA (e.g., tiotropium): onset within 3060 minutes, lasts 24+ hours Anticholinergics are particularly effective in COPD because these patients have increased cholinergic (vagal) tone contributing to bronchoconstriction
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In addition to improving accessibility and agility, DHTs also hold promising potential to improve therapeutic outcomes in rare diseases
