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You can see a table detailing this below and at 1:21 in my video Do Vitamin B12 Supplements Cause Acne

B12 levels can decrease with age, as well as being lower in people who have undergone weight loss surgery, or suffer from pernicious anaemia, Crohns or celiac disease

Arthur Heller, HealthTap There is also the risk of bacterial contamination, which increases as the B12 ages

Moreover, the association between B12 deficiency and psychiatric disorders, mainly depression and psychosis, highlights the crucial role of this vitamin in maintaining mental health (, , )

Retrieved 13 January 2026
