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The molecular mechanisms regulating the KEAP1-NRF2 pathway

As a coenzyme, it participates in the transfer of one carbon unit, thereby playing a role in the biosynthesis of nucleotides and proteins

Exposure to environmental pollutants selects for xenobiotic-degrading functions in the human gut microbiome

Activation of the NRF2/SLC7A11/GPX4 signaling pathway leads to elevated GSH levels, reduced MDA and ROS accumulation, suppression of neuronal ferroptosis, lipid peroxidation, and amino acid antioxidant dysfunction, ultimately mitigating neuronal injury

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