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The gut microbiota is recognized to directly produce neurotransmitters that can affect intestinal function
The decrease of GDH1 activity limits the flow of carbon into TCA cycle (59)

Capacitation, the functional maturation of spermatozoa in the female reproductive tract, requires ROS-mediated activation of intracellular signaling cascades (69)

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Dominant-negative G subunits are a mechanism of dysregulated heterotrimeric G protein signaling in human disease
