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However, bacteria use a range of defense mechanisms to better resist phage infection 7 , which is a recognized issue with phage therapy that has historically limited its potential clinical utility

doi: 10.3390/antiox13070805

(2003) Insulin resistance in the liver-specific IGF-1 gene-deleted mouse is abrogated by deletion of the acid-labile subunit of the IGF-binding protein-3 complex: relative roles of growth hormone and IGF-1 in insulin resistance

Choi, D