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Description

Folate receptor-targeted polymeric micellar nanocarriers for delivery of orlistat as a repurposed drug against triple-negative breast cancer

Faster Healing and Reduced Inflammation With natural hormone declines and reduced collagen production, aging women experience slower tissue repair and flexibility, as well as an increased likelihood of suffering from chronic inflammation, especially when they go through menopause

Wang, T.C

SERT HVA: 4-Hydroxy-3-methoxyphenylacetic acid, Homovanillic acid i.p.: Intraperitoneal ICV: Intracerebroventricular i.v.: Intravenous K e : Elimination constant KO: Knockout LSD: Lysergic acid diethylamide MAO: Monoamine oxidase MAOi: Monoamine oxidase inhibitor MDA: ()-3,4-Methylenedioxyamphetamine MDEA: Methylenedioxyethylamphetamine MDMA: ()-3,4-Methylenedioxymethamphetamine, Ecstasy -MeDA: -Methyldopamine, 3,4-Dihydroxyamphetamine, HHA METH: Methamphetamine 4-MTA: 4-Methylthioampethamine mtDNA: Mitochondrial DNA MPT: Mitochondrial permeability transition NA: Noradrenaline NAC: N-Acetylcysteine NAT: Noradrenaline transporter NMDA: N -methyl-d-aspartic acid N-Me--MeDA: N -methyl--methyldopamine, 3,4-Dihydroxymethamphetamine, HHMA NO : Nitric oxide radical O 2 : Superoxide anion ONOO : Peroxynitrite PET: Positron emission tomography PD: Pharmacodynamic PK: Pharmacokinetic PKC: Protein kinase C p.o.: Per os PMA: p -Methoxyamphetamine RNS: Reactive nitrogen species ROS: Reactive oxygen species s.c.: Subcutaneous -SH: Sulfhydryl SPECT: Single-photon emission computed tomography SOD: Superoxide dismutase SULT: Sulfotransferase t 1/2 : Elimination half-life TH: Tyrosine hydroxylase THC: 9 -Tetrahydrocannabinol T max : Median time to maximum concentration TPH: Tryptophan hydroxylase UGT: UDP-glucuronosyltransferase UK: United Kingdom USA: United States of America VMAT: Vesicular monoamine transporter WT: Wild type References Abourashed EA, El-Alfy AT, Khan IA, Walker L (2003) Ephedra in perspective-a current review