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Description
HP is metabolically reduced in humans, but not in rats and the majority of other experimental animals, with the exception of guinea pigs (Cavia porcellus) (15)
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Submaximal loads and avoidance of the Valsalva maneuver via controlled breathing are recommended (Williams et al., 2007)

Meijers and Evenepoel, 2011)

At the mechanistic level, NCs modulate several signaling pathways, such as PI3K/AKT/mTOR, NF-B, MAPK, and Wnt/-catenin pathways