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In contrast, oral supplementation with acetylcarnitine for one month in old rats does not increase the total energy expenditure, despite the increase in fat utilization as metabolic fuel [99]

This could be due to ALCs quick absorption and capacity to cross the blood-brain barrier, potentially altering the gut microbiota composition and limiting the abundance of TMA-producing bacteria

Wong, A

RossiniMDi MunnoOValentiniGBianchiGBiasiGCacaceEet al

[13] Metabolic defects of fatty acid oxidation [edit] More than 20 human genetic defects in fatty acid transport or oxidation have been identified
