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These results confirm that VacA disrupts TRPML1 activity and causes disruption of lysosomal calcium homeostasis

doi: 10.1021/bi991028u

K.GuS.BobbalaD.LangF

Glycemic Control with Diet, Sulfonylurea, Metformin, or Insulin in Patients with Type 2 Diabetes Mellitus: Progressive Requirement for Multiple Therapies (UKPDS 49)
Indeed, downregulation of CAT protein expression was reported in MASH patients as compared to control (Shearn et al
