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In the scalp, that same signaling reactivates follicles sitting dormant in the resting phase, extending the active growth window and increasing the diameter of the hair shaft itself

In skin tissue, topical administration of rutin inhibited the IMQ-induced increases in reactive oxygen species, nitric oxide, and malondialdehyde, and significantly increased the IMQ-induced decreases in total antioxidant capacity, superoxide dismutase, and glutathione peroxidase