importance of glutathione reductase Frontiers Glutathione-Related Enzymes and Proteins: A

Thiagarajan G, Chandani S, Sundari CS, Rao SH, Kulkarni AV, Balasubramanian D

Zipor G, Oren-Shamir M (2013) Do vacuolar peroxidases act as plant caretakers

Importantly, cells could be protected from ferroptosis by providing exogenous small molecule lipophilic antioxidants (e.g., ferrostatin-1, liproxstatin-1, trolox) and iron chelators (e.g., deferoxamine) that neutralize toxic lipid ROS or decrease the formation of lipid peroxyl radicals [60, 61, 67]

4.1.3 Quercetin Quercetin, a natural flavonoid widely distributed in plants, has been shown to reduce oxidative stress and promote neurogenesis in animal models of ischemic stroke via antioxidant (136), anti-inflammatory (137), and neuroprotective effects (138)

10.1021/bi970805s 35 JohnsonW