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Figure 5 Downstream cellular mediators of Dihexa protection Activation of the receptor tyrosine kinase c-Met leads to the recruitment of many signaling mediators and ultimately the activation of downstream signals, most notably Akt-TOR and Ras-ERK (Organ and Tsao, 2011)

PMID: 36590745

10.1007/s00436-015-4898-9 161 NasirianH

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Keywords: growth hormone, paediatrics, short stature, insulin-like growth factor-I, insulin-like growth factor, binding protein-3 Introduction The growth hormone (GH)insulin-like growth factor (IGF)-I axis is the principle endocrine system regulating linear growth in children (1)