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Brown, B., Mitra, S., Roach, F

[DOI] [PMC free article] [PubMed] [Google Scholar] 31.Monsalves-Alvarez M, Morales PE, Castro-Sepulveda M, Sepulveda C, Rodriguez JM, Chiong M, et al
Similarly, heavy metals such as cadmium, lead, and mercury, often encountered in industrial settings or contaminated water and food supplies, interfere with mitochondrial function and catalyze the production of free radicals [7, 8]

It did suggesting a systemic metabolic problem may be present

Lifestyle interventions represent the foundation of obesity treatment, yet an escalation to pharmacological and/or surgical interventions is often needed
