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MOTS-c treatment significantly (i) improves physical performance in young, middle-age, and old mice, (ii) regulates skeletal muscle metabolism and gene expression, and (iii) enhances adaptation to metabolic stress in C2C12 cells in an HSF1-dependent manner

Authors contributions MP, SO and VVZ take care of medical management of the patients

Lifelong PE was diagnosed by an experienced andrologist on the basis of the International Society of Sexual Medicine (ISSM) definitions 3 , including the evaluation of intravaginal ejaculatory latency time (IELT) by stopwatch 18

(South Bend, IN)

Therefore, it can also help with peripheral vascular disease