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Indeed, there are studies support a correlation between a malfunction of autophagy-related genes and increased susceptibility to Crohns disease

Desvenlafaxine Versus Placebo in the Treatment of Children and Adolescents with Major Depressive Disorder

Kittredge A

With regards to TA, while we found no relationship between pre-treatment levels of TA and antidepressant Responder status, our results raise the possibility that lower baseline TA may be associated with greater absolute improvements in depression severity as well as perceived stress after 8 weeks of SSRI treatment

Srinivasan, R., Ratiney, H., Hammond-Rosenbluth, K