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Description
Most patients experience minimal to no adverse effects
While mitochondria have their own antioxidant defenses, including mitochondrial SOD, these defenses are often insufficient to neutralize the high levels of ROS produced during oxidative phosphorylation, especially if mitochondrial function is compromised
Metabolic activation and hepatotoxicity
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10.1016/S1044-7431(03)00173-8 [DOI] [PubMed] [Google Scholar] Bodnar R
