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Non-enteric-coated preparations of VPA are rapidly and nearly completely absorbed from the gastrointestinal tract, with peak plasma concentrations occurring 14 hours after ingestion [12]
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HO-1 was also found to be involved in a protective effect by inhibiting pyroptosis in diabetic cardiomyopathy [73]
A biopsy is recommended when radiographic examination does not reveal the presence of metal particles, even if clinical suspicion leans towards an amalgam tattoo, particularly in solitary cases, since these lesions enter into differential diagnosis with nevi and melanoma [72]
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