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Inhibitors of HGF/c-Met pathway in cancer therapy The evidence that the HGF/c-Met pathway is involved in the progression and dissemination of several malignancies has generated considerable interest in HGF and Met as major targets in cancer therapy and drug development
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Accordingly, TRZ, a drug with a multi-modal mechanism of action, approved for the treatment of depression in several countries, is suggested as an alternative treatment for pain relief by the NICE Clinical Guideline Neuropathic pain Pharmacological Management [7]
