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Patients with unstable cardiovascular disease, poorly controlled hypertension, or significant hypotension may require additional monitoring or alternative therapies

Giving them more frequently than the established schedule is a form of over-treatment that is not supported by evidence and can strain healthcare resources (nurses time, clinic space, and medication supplies)

E.VisheM.TukachinskyH.ZhengS.-L.LiF.et al (2022)

This short-acting pulsatile effect makes it suitable for once-daily administration to support physiological GH patterns

This might include limiting alcohol intake
