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Studies confirm that 5-Amino-1MQ treatment significantly reduces intracellular levels of the NNMT product 1-MNA while simultaneously increasing NAD+ and SAM concentrations in adipocytes and muscle cells

In obese mice, chronic administration of AOD-9604 was shown to significantly increase 3- adrenergic receptor (3-AR) mRNA expression in both white and brown adipose tissue

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The body downregulates its basal metabolic rate to conserve energy, matching the lower caloric intake induced by the medication