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At institutions like the National University of Natural Medicine, Bastyr University, and the Sonoran University of Health Sciences, students learn to evaluate individual patient factors when developing peptide protocols

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Increased expression of nestin, a marker for neuronal plasticity, in the myenteric plexus suggests active neuroplasticity in response to the loss of intestinal segments

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Intriguingly, quantification of the numbers of neurons in the myenteric plexus of germ-free versus SPF mice revealed a significant reduction in numbers in the duodenum and ileum but not in the colon, which seems somewhat counterintuitive and not readily explicable to this point