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The gut microbiotamasters of host development and physiology

108,109 The decrease in mitochondrial membrane potential induces PINK1 aggregation and autophosphorylation on the outer mitochondrial membrane, which recruits Parkin to initiate the PINK1-Parkin mitophagy pathway to remove damaged mitochondria

Environ Toxicol Pharmacol 74:103312

These also work together to lighten the skin by deactivating the pigment producing enzyme called enzyme tyrosinase
