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Meta-regression with the same variables (year of publication, dosage, and duration) was performed for HDL and LDL analysis

[DOI] [PubMed] [Google Scholar] 38.Brown MS, Goldstein JL

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Finally, delineating tissue-preferential effects is essential to determine whether improvements in IR arise primarily from reduced hepatic lipid content or also involve amelioration of pancreatic steatosis and skeletal muscle lipid metabolism
