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liver being among organs with the highest content ( The concentration of GSH in the mitochondrial compartment is more important for cell survival than the GSH found in the cytosol

In particular, multiplexed edited detection allows for GSH editing simultaneously with others metabolites in a single acquisition

Conclusions As a marker of oxidative stress, cerebral GSH plays a role in cell signaling, protein function, gene expression, cell differentiation, and proliferation in the brain

T., Dudley, V

These drugs differ from prior therapies in that they aim to improve the production, intracellular processing, and/or function of the defective CFTR protein