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When mitochondrial DNA volume and integrity are compromised, free radicals proliferate, and cell damage occurs, leading to accelerated aging and wrinkles

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Both of them can activate ferroptosis by increasing the accumulation of Fe 2+ and MDA while suppressing the expression of GPX4 [71 72]

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Dementia with Lewy bodies is reported as the third leading cause after Alzheimers and vascular dementia

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