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coli strain MG1655 was used as the starting strain to implement metabolic engineering

(FITC: HY-66019

Bae SC, Kim SJ, Sung MK: Impaired antioxidant status and decreased dietary intake of antioxidants in patients with systemic lupus erythematosus

Immunity (2018) 49(1):8092.e7

CTR1 over-expression or functional impairment of ATP7A/7B breaks this loop, allowing copper to accumulate and penetrate mitochondria, thereby priming cuproptosis
