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Through phosphoproteomics analysis and molecular docking, we identified MAPK1 and MAPK3 as potential metformin targets in DKD, with the MAPK signaling pathway being a key enrichment pathway
Cysteine dioxygenase 1 is a tumor suppressor gene silenced by promoter methylation in multiple human cancers
Future studies using proteomics 49 will investigate this axis and the potential for methionine supplementation 41 to fuel protein damage repair
Datis Kharrazian states, Addressing inflammation through diet, lifestyle, and targeted supplementation is crucial for restoring thyroid health
doi: 10.3389/fpls.2023.108276 21 IrzykG
