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Neuroprotection in the Central Nervous System Glutathione (GSH) plays a vital neuroprotective role in the central nervous system (CNS), primarily by regulating redox homeostasis, detoxifying electrophilic compounds, and modulating excitotoxic signaling pathways
GRK2 knockdown in mice exacerbates kidney injury and alters renal mechanisms of blood pressure regulation
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A similar version of this genetic modification was reported also by another lab [64] , and both papers reported that chronically high levels of circulating GDF11 were surprisingly well tolerated in mice
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