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Along with its counteraction of serotonin syndrome (23), as well as Porsolts test-helpless behaviour (17), highly specific alpha-methyl-L-tryptophan autoradiographic measurements reveal that it affects central nervous system neurotransmitters synthesis and function in brain specific regions when it was given peripherally (25)

doi: 10.1080/17425247.2021.1845648 18 Chinese Society of Tuberculosis CMA (2022)

Bhaumik and colleagues [596] demonstrated that Bayesian modeling integrating both structural and functional MRI outperformed univariate approaches in detecting neuroprotective effects, especially in small or heterogeneous samples

More recent investigations into APAP hepatotoxicity have established the critical role of mitochondrial dysfunction in mediating liver injury as well as clarified mechanisms of APAP-induced hepatocyte cell death