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Vitamin B 12 deficiency and neuropsychiatric illness Neuropsychiatric manifestations in the absence of haematological abnormalities are commonly seen in the elderly.2 50 These include paraesthesia, weakness, gait abnormalities, and cognitive or behavioural changes

Analytical Biochemistry 253(2):162168

Once absorbed or synthesized, CoQ10 is distributed to tissues through lipoprotein transport, accumulating primarily in mitochondria, where it plays a crucial role in electron transport and ATP production ( A study investigated the relationship between CoQ10 and female fertility and indicated that CoQ10 can support healthy oocyte development in women, prevent premature ovarian failure, and increase ovarian sensitivity to estrogen, ultimately leading to improved ovarian function ( in vitro fertilization and embryo transfer (IVF-ET) treatment, resulting in a higher success rate of embryo transfer (Zhang et al., 2020)

Moreover, oxidative stress is closely linked to diabetic complications like retinopathy, nephropathy, and cardiovascular diseases [1] (Figure 1)