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Figure 6 4.1 Ferroptosis and DN The pathogenesis of DN involves multiple factors, including dysregulation of glucose and lipid metabolism, oxidative stress, accumulation of advanced glycation end-products (AGEs), inflammation, activation of the innate immune system, genetic susceptibility, activation of the renin-angiotensin system, and miRNAs ( Recently, researchers have identified hub genes (FPR3, C3AR1, CD14, ITGB2, RAC2, and ITGAM) associated with ferroptosis in diabetic kidney disease through gene differential expression analysis in patients

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