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Instead, excess nitrogen is largely transiently stored as glutamine, primarily in astrocytes that are less sensitive to nitrogen stress than neurons (Cooper, 2001
[DOI] [PMC free article] [PubMed] [Google Scholar] 77.Kadowaki T., Isendahl J., Khalid U., Lee S.Y., Nishida T., Ogawa W., Tobe K., Yamauchi T., Lim S., STEP 6 Investigators Semaglutide once a week in adults with overweight or obesity, with or without type 2 diabetes in an east Asian population (STEP 6): A randomised, double-blind, double-dummy, placebo-controlled, phase 3a trial

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Therefore, a true overdose that causes toxicity is extremely rare
