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Once tumor cells reach distant metastatic sites, ZFP281 maintains tumor dormancy and prevents tumor proliferation over extended periods via the induction of the class IIcadherin 11

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In addition, the redox imbalance in the cells of the alveolar epithelium, their apoptosis, the increase in inflammation and, consequently, the alteration of gas exchange, also cause a local increase in angiotensin II levels after the inactivation of the ACE2 receptor by the SARS-CoV-2

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