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S2), however the mutant VadK His422Ala did not autophosphorylate and remained in its apo form (m/z = 52272) (Fig
3-Mercaptopyruvate sulfurtransferase produces hydrogen sulfide and bound sulfane sulfur in the brain

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The upregulation and activation of 7nAChR subsequently activate several signaling pathways, including neuroprotective PI3K/Akt and Nrf2 pathways, then suppression of pro-apoptotic caspase-3, and suppression of NF-B that reduce the expression of proinflammatory cytokines such as IL-1, and TNF- [50, 86]

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