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While supplements do not treat the underlying immune mechanism of APD, they may support histamine regulation and inflammatory balance when used alongside medical care

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DOI: 10.1016/j.etap.2014.04.017 43

The study result has shown that the expression of various enzymes involved in oxidative phosphorylation and ATP production (SLC25A5, ATP5B, ATP5A1) was decreased with time, indicating a gradual mitochondrial dysfunction that could contribute to the development of DKD (45)

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