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In contrast, another oxytocin metabolite, [pGlu4,Cyt6]OT(49), increased sociability dose-dependently following subchronic administration, with effects persisting up to 12 days post-treatment

injections of 100 nmol kg 1 GLP-1MK-801 ( n = 8 mice and n = 4 cages), 300 nmol kg 1 GLP-1MK-801 ( n = 8 mice and n = 4 cages) or vehicle (isotonic saline, n = 7 mice and n = 4 cages) in comparison with vehicle-treated age-matched chow-fed C57BL/6 J mice ( n = 16 mice and n = 8-11 cages) for 14 days

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156 We briefly noted, with regard to the discussion above, that cationic Au(III) porphyrins revealed interaction with DNA, thus variation of multidentate amido complexes of cationic character may potentially act as cytotoxic DNA intercalators

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