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Other children, diagnosed because of an affected sibling, had only mild developmental delays or were asymptomatic [3, 103, 104]

In parallel, several clinical studies were conducted and provided evidence that acetyl-l-carnitine may represent an effective therapeutic option for treating peripheral neuropathies (Table 1) [46,47,48,49,50,51,52]

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These conditions explain the impact of carnitine on lactic acid metabolism

In another study, TMAO levels were increased in patients with stable heart failure and elevated levels were associated with increased risk of death [34]