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[DOI] [PubMed] [Google Scholar] Heo, H

Autophagy is essential for the advancement of metastatic tumor cells when they encounter environmental stimuli such as hypoxia and starvation [101, 149,150,151,152]

Therefore, researchers may expect different results with AOD9604 experimentation, depending on the type of fat cells employed

From a clinical perspective, it suggests that in disease states with high IL-5 (like hypereosinophilic syndromes or active IBD with a type 2 skew), targeting Siglec-8 could be especially effective in depleting pathogenic eosinophils

Since it is present within the cells, it offers cells and its fragile structures first-hand protection from oxidative damage