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doi: 10.1002/jcb.21538

Anti-CCP antibodies possess a very high specificity (usually over 90%) for RA and can often be detected years before clinical symptoms arise (Shmerling & Greisen, 2025)

Further studies incorporating markers such as ezrin, along with assessments of both glutamate and GABA metabolism, will be interesting to determine whether these represent distinct pathological states or alternative expressions of astrocytic dysfunction under stress
At the immune level, butyrate helps the body maintain a balanced inflammatory response in the colon without triggering overactivation

[DOI] [PubMed] [Google Scholar] 50.Spence, J