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Glutathione works as a natural skin brightener by inhibiting tyrosinase, an enzyme involved in melanin production

Although initial studies suggested that GSH depletion was only a byproduct of oxidative stress generated during cell death, recent discoveries suggest that GSH depletion and post-translational modifications of proteins through glutathionylation are critical regulators of apoptosis

Medicube's phospholipid capsules mimic skin structure, so the glutathione reaches deeper layers where brightening is more effective

Moreover, the level of residual labelling of individual peptides positively correlated with their protein half-lives (measured independently in primary human fibroblasts 36 ) (Extended Data Fig