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For patients with impaired renal function, the following adjustments should be made: reduce doses of levofloxacin in patients with creatinine clearances (CrCl) below 50 mL/min

Ilic et al., 2011a

Vitamin B12 is water-soluble, and excess amounts are generally excreted through urine

This is especially true for vegans and vegetarians, as B12 is found mostly in animal products

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