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Longevity pathway activation NAD+ plays a crucial role in activating sirtuins, a family of proteins involved in cellular repair, stress response, and aging

When you're deficient, the symptoms are usually gradual: fatigue, brain fog, low mood, tingling in hands or feet, unexplained weakness

They tend to avoid using these muscles now because of the potential risk of injury to the sciatic nerve

Benfotiamine B1 Not B12 but often combined to relieve nerve pain
