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IgE versus IgG4 production can be differentially regulated by IL-10

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There were three identified SYP-14288 metabolites, M1, M2, and M3, and based on catalytic properties of P450s and changes in the molecule ion m/z , a reduction from -NO 2 to -NH 2 of M1 was inferred to be existent in the SYP-14288 metabolism

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