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Discontinuation, regain, and reinitiation (class-level, semaglutide / tirzepatide) Budini 2026 ( eClinicalMedicine ) pooled regain curve: asymptotic maximum regain 75.3% of lost weight, half-life about 23 weeks, so roughly 60% of the loss returns by 12 months and about 40% is still held at a year

Supplementing with vitamin B12 lowers homocysteine levels and may improve mood, particularly in response to stress

Can optimizing nutrition reduce co-morbid conditions often seen in ASD (like anxiety, attention deficits, or sleep disturbances)