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Loh KP, Ramsdale E, Culakova E, Mendler JH, Liesveld JL, O'Dwyer KM, McHugh C, Gilles M, Lloyd T, Goodman M, Klepin HD, Mustian KM, Schnall R, Mohile SG JMIR cancer

The work, which used the protein insulin-like growth factor-1 (IGF-1), showed that an orally delivered, shelf-stable medication grown in lettuce plants could stimulate the growth of bone-building cells and promote bone regeneration

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Pb has been shown to activate astrocytes and microglia, leading to the release of pro-inflammatory cytokines such as interleukin-1 (IL-1) and tumor necrosis factor-alpha (TNF-) [99]

The accumulation of mtROS can contribute to microvascular dysfunction in CKD patients, suggesting that oxidative stress is the key to vascular calcification in patients with CKD [47]