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[DOI] [PMC free article] [PubMed] [Google Scholar] 30.Jia D, Zheng J, Zhou Y, Jia J, Ye X, Zhou B, Chen X, Mo Y, Wang J

The multifaceted role of ferroptosis in liver disease

This transgenic mouse overexpresses the human amyloid precursor protein (APP) carrying two familial AD mutations: The Swedish mutation (KM670/671NL), which increases total A production by enhancing -secretase cleavage, and the Indiana mutation (V717F), which alters -secretase cleavage to favor production of the more aggregation-prone amyloid-beta 142 peptide (A 142 ) [464467]

[DOI] [PMC free article] [PubMed] [Google Scholar] 117.Bayindir Z.S., Yuksel N